Invasive carp pose substantial economic and ecological damage when populations are widespread in freshwater systems within the United States of America (USA). Resource managers in the USA have a limited number of chemical control tools to selectively remove nuisance fish. The present study examined whether Antimycin-A (antimycin) wax encapsulated microparticles could cause selective lethality to invasive carps in a series of laboratory trials, controlled outdoor pond trials, and an experimental pond trial. Datasets include water quality, fish biometrics, fish survival, yttrium consumption, and antimycin microparticle dissipation data. Any use of trade, firm, or product names is for descriptive purposes only and...