The landscape permeability model represents the structural connectivity of sagebrush ecosystem habitat in the Green River Basin (including ~5-10 km boundary outside of the GRB. This model connects patches of habitat, across the landscape using resistances that represent the degree of human modification and slope (energetic costs), using the Multi-Scale Landscape Permeability model (Theobald et al. 2012; Theobald unpublished). We used two metrics: (a) patch importance and (b) betweeness centrality amongst patches. These metrics were summarized for each HUC12. This dataset represents the vulnerability of sagebrush ecosystem permeability to human modification summarized for each HUC12 watershed within the Green River Basin. The purpose of this dataset is to represent sagebrush patch importance, at a landscape level, the relative structural connectivity or permeability of moving amongst or between patches of sagebrush ecosystem habitat. Although this is not a functional connectivity model for a particular species, it is designed to approximate the permeability of the landscape for species that use predominately sagebrush habitat and that are sensitive to human land uses.