The purpose of this research is to leverage recently developed genomics resources for the New Mexico meadow jumping mouse (Zapus hudsonius luteus) in New Mexico, Arizona, and Colorado to address information gaps about genetic variation currently limiting effective conservation and management. There remain several information gaps about genetic variation within and among the remaining populations. Targeted management programs and conservation for these populations action depend on accurate characterization of population genetics. Furthermore, as actions are initiated, a genetic baseline will be needed for comparative approaches to gauge the effectiveness of management activities. New genomics technologies (next-generation sequencing) now enable unprecedented and exciting options for conservation. Obtaining additional genetics information will assist in understanding the relative uniqueness / importance for different portions of the species range, which could directly impact management and on-the-ground operations.