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The goal of this study was to develop and examine whether a management bait that can be used for selective control of grass carp. Our objectives were to 1) quantify the water-based 24-h LC50 of Antimycin-A for grass carp and rainbow trout, 2) quantify the 96-h LD50 of orally administered Antimycin-A laden bait for grass carp and rainbow trout, 3) quantify the leaching rate of Antimycin-A from the bait in water, and 4) determine if a management bait laden with Antimycin-A will be consumed by grass carp and cause lethality in the laboratory. To meet our objectives, Antimycin-A was encapsulated in a wax microparticle similar to Poole et al. (2018) and incorporated into a rapeseed bait for oral gavage feeding and consumption...