Landscape conservation cooperatives (LCCs) are conservation-science partnerships between the U.S. Fish and Wildlife Service, U.S. Geological Survey (USGS), and other federal agencies, states, tribes, NGOs, universities and stakeholders within a geographically defined area. They inform resource management decisions to address national-scale stressors-including habitat fragmentation, genetic isolation, spread of invasive species, and water scarcity-all of which are accelerated by climate change.