To date, hydrological and ecological models have been developed independently from each other, making their application particularly challenging for interdisciplinary studies. The objective of this project was to synthesize and evaluate prevailing hydrological and ecological models in the South-Central U.S., particularly the southern Great Plains region. This analysis aimed to identify the data requirements and suitability of each model to simulate stream flow while addressing associated changes in the ecology of stream systems, and to portray climate variability and uncertainty. The results and deliverables of this project are expected to include a comprehensive, updated, and systematic report on recent developments in ecosystem hydrology with a focus on freshwater resource management. This synthesis report directly addresses existing needs of the Landscape Conservation Cooperatives (LCCs) by providing information that can be readily used to help understand the effect of climate change and land management on hydrology and associated fish communities.