The Arctic Coastal Plain (ACP) of northern Alaskaconsists of an extremely low gradient, lake-richlandscape that is characterized by a complex networkof aquatic habitats and surface features stronglyinfluenced by permafrost dynamics. Much is unknownabout the form, function, and ecological conditions inthis unique hydrologic setting. Amplified climatechange and landscape responses in the Arctic furthercomplicate the capacity to separate natural variabilityfrom land use effects that may occur with petroleumdevelopment. A comprehensive, multi-disciplinaryreview and analysis of recent studies and initialinventory and monitoring in the Fish Creek watershedon the ACP provided guidance to develop a frameworkfor future aquatic monitoring and integrated research.The result is an established network of stream and lakesites for physical, chemical, and biological datacollection that is intended to be sustainable over a longtermperiod and contribute to understanding Arcticaquatic ecology in the context of climate change andassist science-based land management decisions.