Histopathology of American kestrels (Falco sparverius) sequentially exposed to first and second generation anticoagulant rodenticides
Dates
Publication Date
2018-10-04
Start Date
2018-07-16
End Date
2018-07-23
Citation
Lankton, J.S., 2018, Histopathology of American kestrels (Falco sparverius) sequentially exposed to first and second generation anticoagulant rodenticides: U.S. Geological Survey data release, https://doi.org/10.5066/P9K6U6R4.
Summary
This dataset describes histopathological changes in liver, kidney, heart, skeletal muscle and intestine of captive American kestrels sequentially exposed to first and second generation anticoagulant rodenticides (FGAR and SGAR). The goal of the study was to determine the toxicity of sequential exposure to anticoagulant rodenticides (ARs) by evaluating FGAR-FGAR exposure (7 day chlorophacinone exposure, 7 day recovery, than re-exposure) and SGAR-FGAR exposure (7 day brodifacoum, 7 day recovery, than 7 day exposure to chlorophacinone). Birds were necropsied and examined grossly for hemorrhages or anemia, and liver, kidney, heart, skeletal muscle, and intestine was collected for histopathological evaluation. Tissues were scanned at at [...]
Summary
This dataset describes histopathological changes in liver, kidney, heart, skeletal muscle and intestine of captive American kestrels sequentially exposed to first and second generation anticoagulant rodenticides (FGAR and SGAR). The goal of the study was to determine the toxicity of sequential exposure to anticoagulant rodenticides (ARs) by evaluating FGAR-FGAR exposure (7 day chlorophacinone exposure, 7 day recovery, than re-exposure) and SGAR-FGAR exposure (7 day brodifacoum, 7 day recovery, than 7 day exposure to chlorophacinone). Birds were necropsied and examined grossly for hemorrhages or anemia, and liver, kidney, heart, skeletal muscle, and intestine was collected for histopathological evaluation. Tissues were scanned at at least 100x magnification and all lesions, including hemorrhage, inflammation, and degenerative changes, were described and assigned a morphologic diagnosis with severity, chronicity, and distribution as appropriate.
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Lankton Rattner metadata.xml Original FGDC Metadata
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Rattner AMKE data release.csv
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Purpose
The data were collected to help determine the toxicity of sequential exposure to anticoagulant rodenticides by evaluating first and second generation anticoagulant rodenticides (FGAR and SGAR) and SGAR-FGAR exposure. The results will be included in the publication of the exposure trials.
