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Absorption, distribution, metabolism, and elimination of seed-treatment pesticides following the dosing of Japanese quail (Coturnix japonica)

Dates

Publication Date
Start Date
2016
End Date
2018

Citation

Gross, M.S., Hladik, M.L., and Kuivila, K.M., 2019, Absorption, distribution, metabolism, and elimination of seed-treatment pesticides following the dosing of Japanese quail (Coturnix japonica): U.S. Geological Survey data release, https://doi.org/10.5066/P95PYAEY.

Summary

Japanese quail (Coturnix japonica) were orally dosed with pesticide-treated or control-untreated wheat seeds. Pesticide treated wheat seeds were analytically verified for active ingredients of imidacloprid, metalaxyl, tebuconazole, and fludioxonil. Pesticide and metabolite residues were measured in plasma, liver, brain, kidney, muscle, and excreta of exposed and control birds. Samples were extracted via solid phase extraction, pressurized liquid extraction, or sonication. Clean-up steps included protein precipitation followed by solid phase extraction. All samples were analyzed by liquid chromatography tandem mass spectrometry.

Contacts

Point of Contact :
Michael S Gross
Process Contact :
Michael S Gross
Originator :
Michael S Gross, Michelle L Hladik, Kathryn M Kuivila
Metadata Contact :
Michael S Gross
SDC Data Owner :
California Water Science Center
USGS Mission Area :
Environmental Health
Distributor :
U.S. Geological Survey - ScienceBase

Attached Files

Click on title to download individual files attached to this item.

00_Description of JQTreatedWheat_DataRelease.docx 28.95 KB application/vnd.openxmlformats-officedocument.wordprocessingml.document
01_JQTreatedWheat_DataRelease_WheatSeeds.csv 1.55 KB text/csv
02_JQTreatedWheat_DataRelease_RangeFinding.csv 2.83 KB text/csv
03_JQTreatedWheat_DataRelease_Plasma.csv 8.87 KB text/csv
04_JQTreatedWheat_DataRelease_Liver.csv 8.61 KB text/csv
05_JQTreatedWheat_DataRelease_Brain.csv 7.2 KB text/csv
06_JQTreatedWheat_DataRelease_Kidney.csv 7.23 KB text/csv
07_JQTreatedWheat_DataRelease_Muscle.csv 7.24 KB text/csv
08_JQTreatedWheat_DataRelease_Feces.csv 1.42 KB text/csv
09_JQTreatedWheat_DataRelease_iLOD.csv 384 Bytes text/csv

Purpose

Data were collected as part of a larger study to assess the toxicokinetics of seed treatment pesticides within a model avian species, Japanese quail (Coturnix japonica). The data documents the absorption, distribution, metabolism, and elimination of imidacloprid, metalaxyl, tebuconazole, and fludioxonil following a plausible exposure scenario with pesticide-treated wheat seeds.

Additional Information

Identifiers

Type Scheme Key
DOI https://www.sciencebase.gov/vocab/category/item/identifier doi:10.5066/P95PYAEY

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