A previously published three-dimensional, groundwater model (SUTRA) (http://doi.org/10.3133/sir20135216) was used to evaluate the effects of future climate and withdrawal on the freshwater lens of Guam. The model was run using 2080 to 2099 estimated recharge and sea-level rise. This USGS data release contains all of the input and output files for the simulations described in the associated report "Water resources on Guam—Potential impacts of and adaptive response to climate change: U.S. Geological Survey Scientific Investigations Report 2019-5095" by Gingerich, S.B., Johnson, A.G., Rosa, S.N., Marineau, M.D., Wright, S.A., Hay, L.E., Widlansky, M.J., Jenson, J.W., Wong, C.I., Banner, J.L., Keener, V.W., and Finucane, M.L.(https://doi.org/10.3133/sir20195095). [...]