Conceptually, we overlaid down-scaled Global Climate Model data to assess climatic conditions with fish species thermal tolerance data and potential barrier to movement data to predict future fish species distributions and/or identify species that may be vulnerable to climate projections. These species distribution data, of 13 fish species at 3 different time frames, were constructed from species distribution models containing only current, projected 2050, and projected 2099 air temperature (obtained from The Nature Conservancy Climate Wizard tool) and average United States Geological Survey hydrologic unit-8 daily discharge. Average daily discharge was calculated as the average discharge of all streamgages within a HUC-8. Species point of occurrence data was obtained from the USGS Biodiversity Informatics Serving Our Nation (BISON) database. Based on these inputs, species distribution was then modeled using the MaxLike R package (Chandler and Royale 2013) for the Missouri River Basin.